We are developing and optimising kinetic models of metabolism, pharmacokinetics and signaling. Other types of processes can be addressed depending on the amount of the available information.
Our particular strength is the experience in use of global stochastic optimisation methods in parameter estimation and optimisation tasks. In both cases we are implementing different types of constraints to improve the credibility of results.
Our main modeling tool is the software COPASI. We have used COPASI alone and in combination with COPASI wrapper SpaceScanner to manage parallel optimisation runs of global stochastic optimisation methods.